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1

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

Yamada, Naoya, Karasawa, Tadayoshi, Kimura, Hiroaki, Watanabe, Sachiko, Komada, Takanori, Kamata, Ryo, Sampilvanjil, Ariunaa, Ito, Junya, Nakagawa, Kiyotaka, Kuwata, Hiroshi, Hara, Shuntaro, Mizuta, K

Journal:

Cell Death and Disease

Year:

2020

Language:

english

File:

PDF, 3.59 MB

english, 2020

2

Deep and superficial circumflex iliac arteries and their relationship to the ultrasound-guided femoral nerve block procedure: A cadaver study

Ogami, Keiko, Murata, Hiroaki, Sakai, Akiko, Sato, Shuntaro, Saiki, Kazunobu, Okamoto, Keishi, Manabe, Yoshitaka, Hara, Tetsuya, Tsurumoto, Toshiyuki

Journal:

Clinical Anatomy

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

3

Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis

Sasaki, Yuka, Nakatani, Yoshihito, Hara, Shuntaro

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2015

Language:

english

File:

PDF, 683 KB

english, 2015

4

Association between clinical symptoms and postâmortem neuropathology in dementia with Lewy bodies

Kaneko, Yoshitsugu, Hirao, Kentaro, Serisawa, Shuntaro, Kanetaka, Hidekazu, Shimizu, Soichiro, Hirai, Hideaki, ShishidoâHara, Yukiko, Umahara, Takahiko, Sakurai, Hirofumi, Hanyu, Haruo

Journal:

Geriatrics & Gerontology International

Year:

2020

File:

PDF, 512 KB

2020

5

Clinical Efficacy of Bone Reconstruction Surgery with Frozen Cortical Bone Allografts for Nonunion of Radial and Ulnar Fractures in Toy Breed Dogs

Munakata, Shuntaro, Nagahiro, Yukari, Katori, Daichi, Muroi, Norihiro, Akagi, Hiroyuki, Kanno, Nobuo, Harada, Yasuji, Yamaguchi, Shinya, Hayashi, Kei, Hara, Yasushi

Journal:

Veterinary and Comparative Orthopaedics and Traumatology

Year:

2018

Language:

english

File:

PDF, 550 KB

english, 2018

6

Effect of the hsp90 inhibitor geldanamycin on androgen response of prostate cancer under hypoxic conditions

Yasutomo Suzuki, Yukihiro Kondo, Shuntaro Hara, Ryouji Kimata, Taiji Nishimura

Journal:

International Journal of Urology

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

7

Design, synthesis, and evaluation of Trolox-conjugated amyloid-β C-terminal peptides for therapeutic intervention in an in vitro model of Alzheimer’s disease

Arai, Takuya, Ohno, Akiko, Kazunori, Mori, Kakizawa, Taeko, Kuwata, Hiroshi, Ozawa, Toshihiko, Shibanuma, Motoko, Hara, Shuntaro, Ishida, Seiichi, Kurihara, Masaaki, Miyata, Naoki, Nakagawa, Hidehiko,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 880 KB

english, 2016

8

Apical Hypertrophic Cardiomyopathy Associated With Life-Threatening Paroxysmal Atrial Flutter With a Slow Ventricular Response

Hiasa, Go, Hamada, Mareomi, Kodama, Koji, Watanabe, Sanae, Ohtsuka, Tomoaki, Ikeda, Shuntaro, Hashida, Hidetoshi, Kuwahara, Taishi, Hara, Yuji, Shigematsu, Yuji, Hiwada, Kunio

Journal:

Japanese Circulation Journal

Year:

2000

File:

PDF, 411 KB

2000

9

Role of prostacyclin synthase in carcinogenesis

Sasaki, Yuka, Ochiai, Tsubasa, Takamura, Masaya, Kondo, Yukihiro, Yokoyama, Chieko, Hara, Shuntaro

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2017

Language:

english

File:

PDF, 303 KB

english, 2017

10

Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: Role of NF-E2-related factor-2

Atsuko Sakurai, Michie Nishimoto, Seiichiro Himeno, Nobumasa Imura, Masafumi Tsujimoto, Manabu Kunimoto, Shuntaro Hara

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 358 KB

english, 2005

11

Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models

Shuntaro Hara, Daisuke Kamei, Yuka Sasaki, Akemi Tanemoto, Yoshihito Nakatani, Makoto Murakami

Journal:

Year:

2010

Language:

english

File:

PDF, 669 KB

english, 2010

12

Serum Creatinine Level Underestimates Hypertensive Renal Involvement in Elderly Patients with Essential Hypertension.

Shigematsu, Yuji, Hamada, Mareomi, Hiasa, Go, Sasaki, Osamu, Ohtsuka, Tomoaki, Hashida, Hidetoshi, Ikeda, Shuntaro, Suzuki, Makoto, Hara, Yuji, Hiwada, Kunio

Journal:

Hypertension Research

Year:

1999

Language:

english

File:

PDF, 849 KB

english, 1999

13

Interleukin-21 Gene Transfection Into Mouse Bladder Cancer Cells Results in Tumor Rejection Through the Cytotoxic T Lymphocyte Response

Furukawa, Junya, Hara, Isao, Nagai, Hiroshi, Yao, Akihisa, Oniki, Shuntaro, Fujisawa, Masato

Journal:

The Journal of Urology

Year:

2006

Language:

english

File:

PDF, 389 KB

english, 2006

14

Risk factors for an acute exacerbation of idiopathic pulmonary fibrosis

Kakugawa, Tomoyuki, Sakamoto, Noriho, Sato, Shuntaro, Yura, Hirokazu, Harada, Tatsuhiko, Nakashima, Shota, Hara, Atsuko, Oda, Keishi, Ishimoto, Hiroshi, Yatera, Kazuhiro, Ishimatsu, Yuji, Obase, Yasus

Journal:

Respiratory Research

Year:

2016

Language:

english

File:

PDF, 615 KB

english, 2016

15

Hypoxia-Inducible Factor-3α Functions as an Accelerator of 3T3-L1 Adipose Differentiation

Hatanaka, Misaki, Shimba, Shigeki, Sakaue, Motoharu, Kondo, Yukihiro, Kagechika, Hiroyuki, Kokame, Koichi, Miyata, Toshiyuki, Hara, Shuntaro

Journal:

Biological & Pharmaceutical Bulletin

Year:

2009

Language:

english

File:

PDF, 181 KB

english, 2009

16

Novel Bioassay for the Assessment of Neurotoxicity of Chemicals Based on the Neurite Extension in Human Neuroblastoma NB-1 Cells

Kunimoto, Manabu, Yoshimi, Risa, Matsushita, Sachiko, Sakaue, Motoharu, Takanaga, Hiromi, Hara, Shuntaro, Utsumi, Hideo, Nakasugi, Osami

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2003

Language:

english

File:

PDF, 313 KB

english, 2003

17

[Methods in Enzymology] Phospholipases Volume 197 || [36] Purification of mammalian nonpancreatic extracellular phospholipases A2

Year:

1991

Language:

english

File:

PDF, 453 KB

english, 1991

18

Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway

Tomofumi Fujino, Kaori Murakami, Issei Ozawa, Yoshie Minegishi, Ryo Kashimura, Toshihiro Akita, Susumu Saitou, Takehisa Atsumi, Takashi Sato, Ken Ando, Shuntaro Hara, Kiyomi Kikugawa, Makio Hayakawa

Journal:

Year:

2009

Language:

english

File:

PDF, 472 KB

english, 2009

19

Enhanced antitumor activity of xanthohumol, a diacylglycerol acyltransferase inhibitor, under hypoxia

Keiko Goto, Tomohiro Asai, Shuntaro Hara, Ichiji Namatame, Hiroshi Tomoda, Mamoru Ikemoto, Naoto Oku

Journal:

Year:

2005

Language:

english

File:

PDF, 233 KB

english, 2005

20

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

Kamei, Daisuke, Murakami, Makoto, Sasaki, Yuka, Nakatani, Yoshihito, Majima, Masataka, Ishikawa, Yukio, Ishii, Toshiharu, Uematsu, Satoshi, Akira, Shizuo, Hara, Shuntaro, Kudo, Ichiro

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

21

Cytosolic Prostaglandin E Synthase Is Involved in c-Fos Expression in Rat Fibroblastic 3Y1 Cells

Nakatani, Yoshihito, Miyazaki, Yuki, Hara, Shuntaro

Year:

2017

Language:

english

File:

PDF, 748 KB

english, 2017

22

Very low levels of methylmercury induce cell death of cultured rat cerebellar neurons via calpain activation

Motoharu Sakaue, Maiko Okazaki, Shuntaro Hara

Journal:

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

23

Modulation of telomerase activity by zinc in human prostatic and renal cancer cells

Kaoru Nemoto, Yukihiro Kondo, Seiichiro Himeno, Yasutomo Suzuki, Shuntaro Hara, Masao Akimoto, Nobumasa Imura

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 321 KB

english, 2000

24

Detection and purification of two 14 kDa phospholipase A2 isoforms in rat kidney: their role in eicosanoid synthesis

Shuntaro Hara, Ichiro Kudo, Takeshi Komatani, Katsuhiko Takahashi, Yoshihito Nakatani, Yasuhiro Natori, Mieko Ohshima, Keizo Inoue

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 620 KB

english, 1995

25

Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides

Arai, Takuya, Ohno, Akiko, Mori, Kazunori, Kuwata, Hiroshi, Mizuno, Mirei, Imai, Kohei, Hara, Shuntaro, Shibanuma, Motoko, Kurihara, Masaaki, Miyata, Naoki, Nakagawa, Hidehiko, Fukuhara, Kiyoshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 572 KB

english, 2016

26

Detection of 14-kDa group II phospholipase A2 in human seminal plasma

Kiyoshi Takayama, Shuntaro Hara, Ichiro Kudo, Keizo Inoue

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 679 KB

english, 1991

27

The beneficial effect of beta blockade on cytokine levels in patients with dilated cardiomyopathy

Tomoaki Ohtsuka, Mareomi Hamada, Akiyoshi Ogimoto, Go Hiasa, Osamu Sasaki, Shuntaro Ikeda, Makoto Suzuki, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

28

Ultrasonic 3D Shape Milling for Acrylic Resin Optical Products

Inoue, Shuntaro, Hara, Keisuke

Journal:

Materials Science Forum

Year:

2016

Language:

english

File:

PDF, 747 KB

english, 2016

29

Intestinal fatty acid–binding protein levels in patients with chronic renal failure

Okada, Kyoko, Sekino, Motohiro, Funaoka, Hiroyuki, Sato, Shuntaro, Ichinomiya, Taiga, Murata, Hiroaki, Maekawa, Takuji, Nishikido, Masaharu, Eishi, Kiyoyuki, Hara, Tetsuya

Journal:

Journal of Surgical Research

Year:

2018

Language:

english

File:

PDF, 611 KB

english, 2018

30

Amino Acid Composition and NH2-Terminal Amino Acid Sequence of Human Phospholipase A2 Purified from Rheumatoid Synovial Fluid1

Hara, Shuntaro, Kudo, Ichiro, Matsuta, Kunio, Miyamoto, Terumasa, Inoue, Keizo

Journal:

Journal of Biochemistry

Year:

1988

Language:

english

File:

PDF, 243 KB

english, 1988

31

Vitamin K has the potential to protect neurons from methylmercury-induced cell death In Vitro

Motoharu Sakaue, Naoko Mori, Maiko Okazaki, Erika Kadowaki, Takuya Kaneko, Natsuko Hemmi, Hitomi Sekiguchi, Takehiro Maki, Aisa Ozawa, Shuntaro Hara, Kazuyoshi Arishima, Masako Yamamoto

Journal:

Journal of Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 407 KB

english, 2011

32

Monoclonal antibodies against human synovial phospholipase A2

Kiyoshi Takayama, Ichiro Kudo, Shuntaro Hara, Makoto Murakami, Kunio Matsuta, Terumasa Miyamoto, Keizo Inoue

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 678 KB

english, 1990

33

Subcellular localization and regulation of hypoxia-inducible factor-2α in vascular endothelial cells

Ryo Takahashi, Chie Kobayashi, Yukihiro Kondo, Yoshihito Nakatani, Ichiro Kudo, Manabu Kunimoto, Nobumasa Imura, Shuntaro Hara

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 609 KB

english, 2004

34

Coronary blood flow in hypertensive patients with heart failure

Mareomi Hamada, Taishi Kuwahara, Go Hiasa, Tomoaki Ohtsuka, Shuntaro Ikeda, Hidetoshi Hashida, Shigeki Uemura, Makoto Suzuki, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

35

Sâ1 plus cisplatin with concurrent radiotherapy for locally advanced thymic carcinoma: Study protocol of LOGIK1605/JARTâ1501

Fukuda, Minoru, Funaki, Soichiro, Yamazaki, Takuya, Sato, Shuntaro, Mukae, Hiroshi, Takenoyama, Mitsuhiro, Fukuoka, Junya, Nabeshima, Kazuki, Tateyama, Hisashi, Ashizawa, Kazuto, Hara, Masaki, Seto, T

Journal:

Thoracic Cancer

Year:

2020

File:

PDF, 224 KB

2020

36

Endoscopic Management for Recurrent Hydrocephalus Associated with Neurosarcoidosis

Togashi, Shuntaro, Maruya, Jun, Abe, Hideaki, Nishimaki, Keiichi, Ouchi, Haruka, Hara, Kenju, Tokairin, Takuo, Nishiyama, Kenichi, Shimizu, Hiroaki

Journal:

World Neurosurgery

Year:

2020

File:

PDF, 1.41 MB

2020

37

Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors

Masayasu Urushibara, Junichiro Ishioka, Nobuhiko Hyochi, Kazunori Kihara, Shuntaro Hara, Pratap Singh, John T. Isaacs, Yukio Kageyama

Journal:

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

38

Human Gene Encoding Prostacyclin Synthase (PTGIS): Genomic Organization, Chromosomal Localization, and Promoter Activity

Chieko Yokoyama, Tomoko Yabuki, Hiroyasu Inoue, Yoshinori Tone, Shuntaro Hara, Toshihisa Hatae, Masami Nagata, Ei-Ichi Takahashi, Tadashi Tanabe

Journal:

Year:

1996

Language:

english

File:

PDF, 313 KB

english, 1996

39

Left ventricular geometric patterns and altered force-frequency relations in isolated myocytes from dahl salt-sensitive rats during cardiac remodeling to compensatory hypertrophy

Tomoaki Ohtsuka, Mareomi Hamada, Makoto Suzuki, Akiyoshi Ogimoto, Go Hiasa, Osamu Sasaki, Shuntaro Ikeda, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

40

EPAS1 Promotes Adipose Differentiation in 3T3-L1 Cells

Shimba, Shigeki, Wada, Taira, Hara, Shuntaro, Tezuka, Masakatsu

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 931 KB

english, 2004

41

Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model

Akitake, Yoshiharu, Nakatani, Yoshihito, Kamei, Daisuke, Hosokawa, Masato, Akatsu, Hiroyasu, Uematsu, Satoshi, Akira, Shizuo, Kudo, Ichiro, Hara, Shuntaro, Takahashi, Mitsuo

Journal:

Journal of Neuroscience Research

Year:

2013

Language:

english

File:

PDF, 678 KB

english, 2013

42

Short-Interfering RNA-Mediated Silencing of Thioredoxin Reductase 1 Alters the Sensitivity of HeLa Cells toward Cadmium

Nishimoto, Michie, Sakaue, Motoharu, Hara, Shuntaro

Journal:

Biological & Pharmaceutical Bulletin

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

43

Effects of Selenium Deficiency on Expression of Selenoproteins in Bovine Arterial Endothelial Cells.

HARA, Shuntaro, SHOJI, Yasuko, SAKURAI, Atsuko, YUASA, Kouji, HIMENO, Seiichiro, IMURA, Nobumasa

Journal:

Biological & Pharmaceutical Bulletin

Year:

2001

Language:

english

File:

PDF, 112 KB

english, 2001

44

Antiarrhythmic Drug Cibenzoline Attenuates Left Ventricular Pressure Gradient and Improves Transmitral Doppler Flow Pattern in Patients With Hypertrophic Obstructive Cardiomyopathy Caused by Midventricular Obstruction

Hamada, Mareomi, Shigematsu, Yuji, Inaba, Shinji, Aono, Jun, Ikeda, Shuntaro, Watanabe, Kouki, Ogimoto, Akiyoshi, Ohtsuka, Tomoaki, Hara, Yuji, Higaki, Jitsuo

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 473 KB

english, 2005

45

Analysis on the Substrate Specificity of Recombinant Human Acyl-CoA Synthetase ACSL4 Variants

Shimbara-Matsubayashi, Satoko, Kuwata, Hiroshi, Tanaka, Nobutada, Kato, Masaru, Hara, Shuntaro

Journal:

Biological & Pharmaceutical Bulletin

Year:

2019

Language:

english

File:

PDF, 881 KB

english, 2019

46

Long-chain acyl-CoA synthetase 4 participates in the formation of highly unsaturated fatty acid-containing phospholipids in murine macrophages

Kuwata, Hiroshi, Nakatani, Eriko, Shimbara-Matsubayashi, Satoko, Ishikawa, Fumihiro, Shibanuma, Motoko, Sasaki, Yuka, Yoda, Emiko, Nakatani, Yoshihito, Hara, Shuntaro

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2019

File:

PDF, 10.27 MB

2019

47

Comparison of the effect of beta-blocker on natriuretic peptides in patients with dilated cardiomyopathy with atrial fibrillation versus sinus rhythm

Yuji Hara, Mareomi Hamada, Yuji Shigematsu, Makoto Suzuki, Shuntaro Ikeda, Osamu Sasaki, Tomoaki Ohtsuka, Go Hiasa, Akiyoshi Ogimoto, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999

48

Acetylcholine esterase is a regulator of GFAP expression and a target of dichlorvos in astrocytic differentiation of rat glioma C6 cells

Ozawa, Aisa, Kadowaki, Erina, Haga, Yosuke, Sekiguchi, Hitomi, Hemmi, Natsuko, Kaneko, Takuya, Maki, Takehiro, Sakabe, Kou, Hara, Shuntaro, Yamamoto, Masako, Arishima, Kazuyoshi, Sakaue, Motoharu

Journal:

Year:

2013

Language:

english

File:

PDF, 1.13 MB

english, 2013

49

Ischemia in the Territory of the First Major Septal Perforator Branch Anomalously Originating From the First Diagonal Branch Leads to a Transient Leftward Shift of the QRS Axis in the Frontal Plane

Kodama-Takahashi, Koji, Suzuki, Jun, Watanabe, Akira, Ohtsuka, Tomoaki, Hashida, Hidetoshi, Ikeda, Shuntaro, Kuwahara, Taishi, Hara, Yuji, Shigematsu, Yuji, Hamada, Mareomi, Hiwada, Kunio

Journal:

Circulation Journal

Year:

2003

Language:

english

File:

PDF, 391 KB

english, 2003

50

Augmentation of Prostaglandin E2 Production by Mammalian Phospholipase A2 Added Exogenously1

Hara, Shuntaro, Kudo, Ichiro, Inoae, Keizo

Journal:

Journal of Biochemistry

Year:

1991

Language:

english

File:

PDF, 268 KB

english, 1991

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